Graeme is currently Professor of Pharmacology at the University of Bristol. His research interest is in the mechanisms underlying the development of tolerance to the behavioural effects of opioid drugs and how such tolerance can be reduced by other drugs of abuse  leading to increased risk of overdose and death. His laboratory is currently investigating how fentanyl and related opioids analogues produce their potent and deadly effects. He is a member of the Home Office’s Advisory Council on the Misuse of Drugs and of Drug Science, an organisation that aims to provide unbiased scientific information on drugs.